Thursday, April 2, 2015

3-D neural structure guided with biocompatible nanofiber scaffolds and hydrogels

Damage to neural tissue is typically permanent and causes lasting disability in patients, but a new approach has recently been discovered that holds incredible potential to reconstruct neural tissue at high resolution in three dimensions. It demonstrated a method for embedding scaffolding of patterned nanofibers within three-dimensional hydrogel structures, and it was shown that neurite outgrowth from neurons in the hydrogel followed the nanofiber scaffolding by tracking directly along the nanofibers, particularly when the nanofibers were coated with a type of cell adhesion molecule called laminin.

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